General information

Tritace contains a potent ingredient called Ramipril. It belongs to the group of angiotensin converting enzyme (ACE) inhibitors. It is aimed to decrease the production of angiotensin II and also to reduce the breakdown of bradykinin; therefore it relaxes arterial muscles and amplifies the arteries allowing the heart to pump blood more easily. Ramipril is converted to the active metabolite ramiprilat by liver esterase enzymes. It is used to treat hypertension and congestive heart failure; it prevents heart attacks, diabetic nephropathy with microalbuminuria, and a risk of myocardial infarction in patients over 55 years old. It reduces proteinuria and prevents kidney diseases in patients with nephropathies.

Directions

You need to consult a doctor regarding the appropriate dosage intake. Do not give up taking the medicine unless it is permitted by your doctor. Usually the standard dose of Tritace is 2.5-20 mg taken daily as a single dose or divided into two smaller portions.

Precautions

Before taking Tritace consult your doctor if you are pregnant or plan to be pregnant. This medicine can excrete into the breast milk. Discuss all potential benefits and disadvantages while being treated with Tritace if you are breastfeeding. Inform your doctor if you have ever suffered from cardiac insufficiency, strokes, severe renal failure, hypotension, low or high level of potassium, lupus, diabetes, scleroderma, asthma, glaucoma, Marfan syndrome (a hereditary disorder of connective tissue), Sjogren's syndrome (degeneration of the salivary and lachrymal glands), rheumatoid arthritis. Follow your doctor's instructions about the type and amount of liquids you should drink.

Contraindications

This medication is contraindicated in patients that are hypersensitive to ramipril or any other ACE inhibitors or suffered from angioedema (while being treated with ACE inhibitors), lupus, scleroderma; kidney or liver diseases; mineral disbalance that involves high potassium or low sodium levels in the blood.

Possible side effect

In case you suffer from allergy that involves hives, face swelling, breathe diminishing, muscle pain, nausea or emesis, morbidity, urine color changing, high fever, chest pain, palpitations, a feeling of extreme dizziness or fainting you need to immediately notify your health care practitioner. There can be less serious side effects that are transient and may involve headache, dizziness, lightheadedness, weakness, numbness, tingling in the hands, feet, arms, or leg, digestive upsets, itching, rash, hyperhidrosis. If any of these symptoms persist or worsen, notify your doctor promptly.

Drug interactions

Tritace is able to interact with following medicines: with a class of potassium supplements such as K-Dur, Klor-Con; with salt substitutes that contain potassium; with a group of water pills (diuretics) such as triamterene (Dyrenium, Maxzide, Dyazide), spironolactone (Aldactone), or amiloride (Midamor), hydrochlorothiazide (HCTZ, HydroDiuril, others); lithium (Lithobid, Eskalith, others); digoxin (Lanoxin); indomethacin (Indocin); with a class of nonsteroidal anti-inflammatory drugs; medications used to affect the bone marrow; gold injections; heparin; products that may increase your potassium level; pseudoephedrine; trimethoprim-containing medications. In case you are already taking one of these medications, you need to adjust Tritace dosage schedule with your health care practitioner.

Missed dose

In case you have missed to take a dose of this medication, take it as soon as possible. If you are already supposed to take the next dose, do not take the dose you forgot and keep your ordinary dosing schedule. If you have missed to take a few doses in succession, you should immediately consult your doctor about follow-up actions.

Overdose

If you suspect you have used too much of this medication, seek emergency medical attention right away. You must do this even if symptoms of discomfort or poisoning haven’t been indicated at once. You may need urgent medical attention. Most regular symptoms of overdose involve dizziness, fainting, lassitude, excessive low blood pressure.

Storage

This medication should be stored at room temperature of 15-30 degrees C (59-86 F) away from light, heat and moisture. Avoid storing it in the bathroom. Keep all drugs away from reach of children and pets. Do not use any remnants of the product after the expiry date.

Note

The information presented at the site has a general character. Note please this information cannot be used for self-treatment and self diagnosis. You should consult with your doctor or health care adviser regarding any specific instructions of your condition. The information is reliable, but we concede it could contain mistakes. We are not responsible for any direct, indirect, special or other damage caused by use of this information on the site and also for consequences of self-treatment.