General information

Naprelan belongs to the class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used to relieve pain from various conditions. It also reduces pain, swelling, and joint stiffness caused by arthritis, bursitis, and gout attacks. It works by blocking your body's production of certain natural substances that cause inflammation.

Directions

Take Naprelan exactly as prescribed by your doctor. The recommended starting dose is 750 mg taken once daily. The maximum daily dose is 1,500 mg. The lowest dose needed to control pain and inflammation should be used. Naprelan helps to relieve pain in about 30 minutes. The recommended starting dosage for most people with rheumatoid arthritis, osteoarthritis, or ankylosing spondylitis is 500 mg once a day. Naprelan should be taken with a glass of water. Taking it with milk or food may prevent an upset stomach.

Precautions

Before taking Naprelan you should talk with your doctor if you have asthma, heart disease, congestive heart failure, high blood pressure (hypertension), liver disease, liver failure, kidney disease, kidney failure, bleeding problems, diabetes, stomach ulcers, stomach bleeding, any allergies. Let your doctor know if you smoke or drink alcohol frequently. Alcohol can affect the way the liver works, indirectly affecting the Naprelan. This drug may make you dizzy or drowsy. Do not drive or perform tasks that require alertness. It is not recommended for children under the age of 18 years old. Elderly people may be at a greater risk for side effects while taking this drug.

Contraindications

Do not take Naprelan if you are allergic to naproxen or any ingredients of the medication, are pregnant (third trimester) or breastfeeding, or if you have a bleeding disorder, asthma, itchy skin rash, or allergic reactions after taking acetylsalicylic acid or NSAIDs, active stomach bleeding, bleeding in the brain, high blood potassium (hyperkalemia), inflammatory bowel disease, heart bypass surgery, severe, uncontrolled heart failure, decreased liver function or active liver disease, decreased kidney function or worsening kidney disease.

Possible side effect

Get emergency medical help if you have nausea, dizziness, lightheadedness, abdominal pain, headache, constipation, diarrhea, heartburn, drowsiness, blurred vision, changes in hearing, ringing in the ears, rash, itching, hives, unusual tiredness, pale skin, fast heartbeat, unusual bleeding, changes in weight, thoughts of suicide, fever, chills, stiff neck, dark urine, loss of appetite, pale stools, yellowing of the skin or eyes, cough, difficulty swallowing, hoarseness, bladder pain, painful urination, loss of bladder control, decrease in the amount of urine, swelling of the face and throat, peeling, blistering, chest pain, irregular heartbeat, fast pulse, irregular breathing, trouble sleeping. If you notice other effects not listed above, contact your doctor.

Drug interactions

Tell your doctor about all other medications you use, especially: ACE inhibitors (lisinopril, enalapril, quinapril, benazepril), cyclosporine, angiotensin II receptor blockers (eposartan, losartan, valsartan, telmisartan), beta blockers (betaxolol, propranolol, metoprolol), diuretics (furosemide, torsemide, bumetanide), steroids (prednisone, hydrocortisone, prednisolone), digoxin, lithium, blood thinners (heparin, enoxaparin, dalteparin, ardeparin, fondaparinux, tinzaparin), thrombolytics (streptokinase, alteplase, reteplase), nonsteroidal anti-inflammatory drugs (celecoxib, ibuprofen, indomethacin), methotrexate, SSRI or SNRI medications (duloxetine, citalopram, fluvoxamine, milnacipran). Interaction between two medications does not always mean that you must stop taking one of them. Tell your doctor or prescriber about all prescription, over-the-counter, and herbal medications you are taking.

Missed dose

Take the missed dose as soon as possible. Skip the missed dose if it is time for your next scheduled dose. Don't take extra medicine to make up the missed dose.

Overdose

If you think you have overdosed the medicine seek emergency medical help at once. The overdose symptoms are bloody stools, vomit, nausea, trouble breathing, stupor, drowsiness.

Storage

Store the medicine at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store the drugs in the bathroom. Keep all drugs away from reach of children and pets.

Note

The information presented at the site has a general character. Note please this information cannot be used for self-treatment and self diagnosis. You should consult with your doctor or health care adviser regarding any specific instructions of your condition. The information is reliable, but we concede it could contain mistakes. We are not responsible for any direct, indirect, special or other damage caused by use of this information on the site and also for consequences of self-treatment.